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Five Axially Chiral Ligand Kits Newly Released
Five Axially Chiral Ligand Kits Newly Released1.1 Axially Chiral Ligands: Core Catalytic Scaffolds for Asymmetric Synthesis Axially chiral ligands construct well‑defined chiral cavities via atropisomerism of binaphthyl and biphenyl backbones. They coordinate efficiently with noble metals includi
Updated on 08.21
Imidazole-Based N-Heterocyclic Carbene (NHC) Ligand Kit
Imidazole-Based N-Heterocyclic Carbene (NHC) Ligand Kit1.1 Background & Core Advantages of Imidazole NHC Ligands In 1991, American chemist Anthony J. Arduengo achieved the first stable isolation of free imidazole-type N-heterocyclic carbenes (NHCs), overturning the conventional view that carbenes only ex
Updated on 08.11
Pd-Catalyzed Asymmetric Dearomative Heck/Tsuji-Trost Difunctionalization of Naphthalenes
Pd-Catalyzed Asymmetric Dearomative Heck/Tsuji-Trost Difunctionalization of Naphthalenes1. English Official Research Introduction (Global Website Version) Aromatic compounds are abundant fundamental feedstocks in organic synthesis and medicinal chemistry. Driven by the modern drug design concept of “escaping planar molecules”, dearomati
Updated on 07.24
Photocatalytic Conversion of Aminocyclopropanes to γ‑Lactams by Sequential Ring-Expansion and Peripheral Diversification
Photocatalytic Conversion of Aminocyclopropanes to γ‑Lactams by Sequential Ring-Expansion and Peripheral Diversification 1. English Official Research Brief (Global Website Version) Cyclic frameworks are fundamental structural backbones of pharmaceuticals, agrochemicals and functional materials. Skeletal ring expansion serves as a powerful skeleton-editing strategy
Updated on 07.20
Cobalt-Catalyzed Migratory E-Selective Asymmetric Aza-Nozaki–Hiyama–Kishi Coupling
Cobalt-Catalyzed Migratory E-Selective Asymmetric Aza-Nozaki–Hiyama–Kishi CouplingPublication Information Journal: Angewandte Chemie International EditionArticle Type: Hot PaperDOI: 10.1002/anie.8611979Publication Year: 2026Research Group: Prof. Shaolin Zhu & Dr. Yu Wang Group, Nanjing UniversityAuthors: Yi Wang, Yougui Luo, Lifu
Updated on 07.08
Metal Iridium Photocatalyst in Photodriven SmI2-Catalyzed Asymmetric Ketyl-Olefin Coupling
Metal Iridium Photocatalyst in Photodriven SmI2-Catalyzed Asymmetric Ketyl-Olefin CouplingResearch Background Samarium(II) iodide (SmI2) is an important single-electron reductant in organic synthesis, traditionally used in (super)stoichiometric amounts. Although catalytic applications have been achieved in recent years, catalytic asymme
Updated on 04.29
New Applications of Sadphos Ming-Phos Ligands
New Applications of Sadphos Ming-Phos LigandsResearch Background The chiral gem-diaryl motif is a core scaffold in numerous natural products and drug molecules. The γ,γ-diaryl carbonyl skeleton, in particular, plays a key role in the synthesis of pharmaceuticals such as integrin receptor inhibi
Updated on 04.08
Copper-Photoredox Catalyzed Enantioselective S-Alkylation of Sulfenamides
Copper-Photoredox Catalyzed Enantioselective S-Alkylation of SulfenamidesCopper-Photocatalyzed Enantioselective S-Alkylation of Sulfenamides Enabled by Amino-Acid-Derived N,N,N-Tridentate Ligand Xiangyu Zhuang, Xiao Sun, Yirui Zou, Jun Liu, Gang Zhao, and Hongyu Wang* Chiral sulfinamides are valuable sulfur-stereogenic un
Updated on 04.02
New Applications of Chiral Bisoxazoline Ligands in Nickel-Catalyzed Asymmetric Reactions – Research by University of Cincinnati Liu Wei / Purdue University Tian Shiliang Team in Nat. Catal.
New Applications of Chiral Bisoxazoline Ligands in Nickel-Catalyzed Asymmetric Reactions – Research by University of Cincinnati Liu Wei / Purdue University Tian Shiliang Team in Nat. Catal.Abstract Nickel-catalyzed enantioconvergent cross-coupling is a crucial strategy for constructing stereodefined C(sp³) centers. However, such reactions have long relied on Ni⁰/Niᴵᴵ catalytic cycles, are only compatible with electron-rich nucleophiles
Updated on 03.24
Photodriven Samarium-Catalyzed Asymmetric Ketyl-Olefin Coupling
Photodriven Samarium-Catalyzed Asymmetric Ketyl-Olefin CouplingResearch Background​ Samarium(II) iodide (SmI₂) is an important single-electron reductant in organic synthesis. Traditionally used in (super)stoichiometric amounts, its catalytic applications have been achieved in recent years. However, asymmetric re
Updated on 03.17
Fudan University Zhang Junliang / Zhang Zhanming Team, Nat. Commun.: New Applications of Sadphos-Ming-Phos
Fudan University Zhang Junliang / Zhang Zhanming Team, Nat. Commun.: New Applications of Sadphos-Ming-PhosAsymmetric Synthesis of Heteroatom-Bridged [3.2.1]Octane Scaffolds via Enantioselective β-H Elimination Reaction Fudan University Zhang Junliang / Zhang Zhanming Team, Nat. Commun.: New Applications of Sadphos-Ming-Phos Nature Communicationshttps://d
Updated on 03.04
High-Performance Yellow Luminescent Material TBRB
High-Performance Yellow Luminescent Material TBRBTBRB (2,8-di-tert-butyl-5,11-bis(4-tert-butylphenyl)-6,12-diphenyltetracene) is a high-performance yellow luminescent material. Leveraging its excellent optoelectronic properties and molecular stability, it serves as a core functional material for OL
Updated on 03.02
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